Supramolecular photosensitizers using extended macrocyclic hosts for photodynamic therapy with distinct cellular delivery
Xiuli Zheng, Sheng‐Nan Lei, Zekun Gao, Xiangyu Dong, Hongyan Xiao, Weimin Liu, Chen‐Ho Tung, Li‐Zhu Wu, Pengfei Wang, Huan Cong
Abstract
Two hydrophilic macrocycles can strongly bind hypocrellin B. The resulting supramolecular photosensitizers show excellent photodynamic efficiency with different cellular delivery.
Topics & Concepts
Photodynamic therapySupramolecular chemistryPhotosensitizerChemistryBiocompatibilityConjugated systemAqueous solutionFluorescenceCombinatorial chemistryPhotochemistryMoleculeOrganic chemistryPhysicsPolymerQuantum mechanicsPorphyrin and Phthalocyanine ChemistryPhotodynamic Therapy Research StudiesNanoplatforms for cancer theranostics