How to measure left ventricular myocardial work by pressure–strain loops
Otto A. Smiseth, Erwan Donal, Martin Pěnička, O J Sletten
Abstract
Myocardial work is calculated from non-invasive left ventricular pressure and strain by speckle tracking echocardiography. Myocardial work provides diagnostic information beyond what is achieved from left ventricular ejection fraction and strain since it incorporates afterload, and provides a measure of myocardial efficiency. The method can be used to calculate global as well as segmental work. The work method was recently shown to be of clinical value in selection of patients for cardiac resynchronization therapy. Several other clinical applications are currently tested.
Topics & Concepts
AfterloadCardiologyInternal medicineSpeckle tracking echocardiographyEjection fractionCardiac resynchronization therapyWork (physics)Strain (injury)MedicineVentricular pressureHeart failureBlood pressurePhysicsThermodynamicsCardiac pacing and defibrillation studiesCardiovascular Function and Risk FactorsCardiomyopathy and Myosin Studies