Inhibition of histone lysine demethylase 6A promotes chondrocytic activity and attenuates osteoarthritis development through repressing H3K27me3 enhancement of Wnt10a
Wei‐Shiung Lian, Re‐Wen Wu, Jih‐Yang Ko, Yushan Chen, Shaoyu Wang, Holger Jahr, Feng‐Sheng Wang, Feng‐Sheng Wang
Topics & Concepts
AggrecanEpigenomeCell biologyDemethylaseEpigeneticsChondrocyteCartilageOsteoarthritisHistoneExtracellular matrixHistone methylationChemistryCancer researchGene expressionDNA methylationBiologyMedicineAnatomyPathologyBiochemistryGeneArticular cartilageAlternative medicineOsteoarthritis Treatment and MechanismsKnee injuries and reconstruction techniquesCancer-related gene regulation