β-cyclodextrin chitosan-based hydrogels with tunable pH-responsive properties for controlled release of acyclovir: design, characterization, safety, and pharmacokinetic evaluation
Nadia Shamshad Malik, Mahmood Ahmad, Mohammed S. Alqahtani, Arshad Mahmood, Kashif Barkat, Muhammad Tariq Khan, Ume Ruqia Tulain, Ayesha Rashid
Abstract
bodyweight. Hence, developed hydrogel formulation could be used as potential candidate for controlled drug delivery of an antiviral drug acyclovir.
Topics & Concepts
Self-healing hydrogelsChitosanCyclodextrinMaterials sciencePharmacokineticsCharacterization (materials science)Controlled releaseChemical engineeringNanotechnologyChromatographyPharmacologyChemistryOrganic chemistryPolymer chemistryMedicineEngineeringAdvanced Drug Delivery SystemsHydrogels: synthesis, properties, applicationsRNA Interference and Gene Delivery