Transition-Metal-Free O-Arylation of Alcohols and Phenols with <i>S</i>-Arylphenothiaziniums
Tatsuki Yoshida, Yuki Honda, Tatsuya Morofuji, Naokazu Kano
Abstract
Herein, we report the transition-metal-free O-arylation of alcohols and phenols with S-arylphenothiaziniums, which can be easily synthesized from boronic acids. Aryl substituents derived from arylboronic acids were selectively introduced into the hydroxy groups in alcohols and phenols, and a variety of aryl ethers were synthesized. This selectivity is supported by theoretical calculations.
Topics & Concepts
PhenolsChemistryArylTransition metalOrganic chemistrySelectivityCatalysisAlkylCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques