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Cervical longitudinally extensive myelitis after vaccination with inactivated virus-based COVID-19 vaccine

Mahsa Sepahvand, Narges Yazdi, Mohammad Rohani, Maziar Emamikhah

2021Radiology Case Reports18 citationsDOIOpen Access PDF

Abstract

Myelitis, including longitudinally extensive transverse myelitis (LTEM), is reported in more than forty patients after coronavirus disease 2019 (COVID-19). Among COVID-19 vaccines, only Oxford-AstraZeneca COVID-19 vaccine (AZD1222) has been associated with few cases of myelitis (1 LTEM). We report the first case of myelitis/LTEM after BBIBP-CorV/Sinopharm vaccine, interestingly presented as a hemicord syndrome. A 71-year-old male presented with left-side diplegia, right-side hemihyposthesis with facial sparing and impaired position sensation in left foot after vaccination with BBIBP-CorV. MRI revealed a longitudinal signal in left cervical hemicord. This is the first reported myelitis and LTEM with COVID-19 vaccines other than AZD1222.

Topics & Concepts

MedicineMyelitisTransverse myelitisVaccinationCoronavirus disease 2019 (COVID-19)Multiple sclerosisVirologyInternal medicineSpinal cordImmunologyDiseaseInfectious disease (medical specialty)PsychiatryPeripheral Neuropathies and DisordersMultiple Sclerosis Research StudiesRheumatoid Arthritis Research and Therapies
Cervical longitudinally extensive myelitis after vaccination with inactivated virus-based COVID-19 vaccine | Litcius