Litcius/Paper detail

Design, synthesis and in silico insights of novel 1,2,3-triazole benzenesulfonamide derivatives as potential carbonic anhydrase IX and XII inhibitors with promising anticancer activity

Marwa M. Abdelhakeem, Martha M. Morcoss, Dina Hanna, Phoebe F. Lamie

2024Bioorganic Chemistry16 citationsDOI

Topics & Concepts

ChemistryADMECarbonic anhydraseLipinski's rule of fiveAcetazolamideCell cultureDocking (animal)StereochemistryIn silicoIC50In vitroEnzymeBiochemistryBiologyGeneMedicineNursingGeneticsAnesthesiaEnzyme function and inhibitionSynthesis and Catalytic ReactionsPhenothiazines and Benzothiazines Synthesis and Activities
Design, synthesis and in silico insights of novel 1,2,3-triazole benzenesulfonamide derivatives as potential carbonic anhydrase IX and XII inhibitors with promising anticancer activity | Litcius