Innovations in implantation techniques of ventricular assist devices

Abstract

Central MessageThe third generation of ventricular assist devices has led to the development of multiple new implantation techniques. However, novel technologies are needed to further advance the field of mechanical circulatory support devices.See Commentaries on pages 33 and 35.Innovation is defined as the production, adoption, or integration of a value-added novelty.1Schumpeter J.A. Opie R. Elliott J.E. The Theory of Economic Development: An Inquiry into Profits, Capital, Credit, Interest, and the Business Cycle. Transaction Publishers, New Brunswick, NJ1983Google Scholar The most common definitions of innovations describe 4 subtypes in which innovations can be categorized: (1) basic research, (2) breakthrough innovation, (3) sustaining innovation, and (4) disruptive innovation.1Schumpeter J.A. Opie R. Elliott J.E. The Theory of Economic Development: An Inquiry into Profits, Capital, Credit, Interest, and the Business Cycle. Transaction Publishers, New Brunswick, NJ1983Google Scholar,2Henderson R.M. Clark K.B. Architectural innovation: the reconfiguration of existing product technologies and the failure of established firms.Adm Sci Q. 1990; 35: 9-30Crossref Google ScholarTechnological and surgical innovations are greatly interdependent, and some medical specialties, such as mechanical circulatory support (MCS) systems, are especially technology-driven. Habitually innovative developments, such as the miniaturization of devices, lead to the establishment of new implantation strategies. Contrarily, the constant longing of physicians for solutions for surgical or clinical challenges and patients' preferences drive engineers to adapt and reinvent technological devices.A breakthrough innovation in the development of MCS was the shift from pulsatile-flow to continuous-flow pumps, which facilitated the miniaturization of ventricular assist devices (VADs).3Hanke J.S. of the Google Scholar the of devices to the new generation of devices has the of the implantation and has facilitated implantation as a sustaining J.S. of the Google of a as a ventricular assist a Google ventricular assist Google of a for a ventricular assist the clinical Google Scholar The of technological devices, implantation and greatly to the of the new generation of and in the for a in Google innovative as as surgical for implantation and the the most for implantation was a a for the techniques. has the most in and has the a in Google Scholar However, the of the the of the the miniaturization of the development of J.S. of the Google of a for a ventricular assist the clinical Google for implantation of Google of a surgical for implantation of ventricular assist devices in on Google of ventricular assist implantation on of (3) Google most a of a and a the the J.S. of the Google of a as a ventricular assist a Google ventricular assist Google of a for a ventricular assist the clinical Google Scholar is the of and a J.S. of the Google for implantation of Google ventricular assist implantation Google Scholar and of implantation are in and of ventricular assist to in and for and on in a new of implantation is the of the from the in to and of Scholar in the such as the innovative implantation J.S. of the Google of a as a ventricular assist a Google ventricular assist Google Scholar is the most and the the of the in ventricular assist Google patients' for multiple implantation is failure and of of and especially in is to be a in and to in J.S. of the Google of a for a ventricular assist the clinical Google for implantation of Google of ventricular assist implantation on of (3) Google of for the implantation of a ventricular assist Google ventricular assist implantation ventricular Google Scholar is are for implantation to the of implantation and for the of the is to the J.S. of the Google Scholar has the most and in However, in for are for are the and of the or of the and and surgical J.S. of the Google J.S. ventricular assist implantation to the Google J.A. implantation of the to the Google for ventricular assist Google Scholar to the the the of the in such as J.S. of ventricular assist implantation of the the Google novel the to the to the a implantation of ventricular assist and (3) Google Scholar surgical is the the of the of implantation has and further implantation be a innovative in the implantation of ventricular assist and (3) Google and to the implantation and the of are a surgical in MCS and of to be a J.S. of the Google a in Google J.S. of ventricular assist to Google Scholar has the to a is and as J.S. of ventricular assist to Google Scholar the and of the pumps, the to to a generation of a J.S. of ventricular assist to Google of is a in in of can be a the the and ventricular was for for is An to is the or or a J.S. new for of ventricular assist Google J.S. of a ventricular assist (4) Google and further or can be of the However, such are of the such as and which can be techniques. the to the ventricular in and or or is in for the of a such as or of J.S. of the Google J.S. ventricular assist Google R. ventricular assist (4) Google implantation of ventricular assist Google ventricular assist devices in is However, such as or the of generation in the is the implantation of in the of a The Google J.S. of in the of a (1) Google Scholar is a surgical as in of However, to the of in is in most An to implantation is the of devices in a implantation has in and further The Google J.S. of in the of a (1) Google of to as a Google to and are a development surgical and specialties, and and are the of a implantation a is a in especially in or implantation is a for in is and the of to are to in and surgical for the of the new the for the of new surgical is to the of of the and can be be can be to be and is be is of implantation be to for on in surgical the of a third generation of However, further surgical innovation be the new disruptive or breakthrough innovations new from the technological the the for has and innovation, the of is in the for technologies are in development or for and of the for innovative technologies to can be are to breakthrough or disruptive innovation to surgical further novel technological and for The innovations in implantation in are in of innovations in surgical implantation of ventricular assist on and R.M. Clark K.B. Architectural innovation: the reconfiguration of existing product technologies and the failure of established firms.Adm Sci Q. 1990; 35: 9-30Crossref Google miniaturization of lead to implantation such as the and devices, and the for devices and the J.S. of the (1) Google mechanical support the as in Google Scholar of for devices the of further surgical and for in the miniaturization of is The of devices be a disruptive innovation implantation be to implantation and surgical of the which to and of the the in which is a of the innovative R. of a a continuous-flow ventricular assist Google Scholar and on the of established are needed to the of novel new implantation techniques. new the for new surgical to innovative is a new to which greatly the and the for ventricular J.S. new for of ventricular assist Google J.S. of a ventricular assist (4) Google Scholar technological in implantation the to the and of the as as for of and the of devices the for ventricular and the further of which lead to of such as and has further needed to implantation is the development of surgical which to implantation in as as a to of the novel such as devices, are in in surgical and to implantation for and the development of such as and devices, further in the of surgical such as the and implantation be technological the for and the of and on the challenges the of for implantation of Google Scholar However, is a which is on the are the of is a and as to especially in as as for the for J.S. of the Google disruptive innovation in the field of mechanical support of is a product the be such a disruptive innovative a in the of failure the innovations in in Google are the of failure The miniaturization of has led to the development of new surgical implantation are especially in However, surgical is and the was in is for further breakthrough innovations such as devices, further novel and surgical lead to further in implantation of and as for and and as for of and to of and to or for which a of The and of of The third generation of ventricular assist devices has led to the development of multiple new implantation techniques. However, novel technologies are needed to further advance the field of mechanical circulatory support The third generation of ventricular assist devices has led to the development of multiple new implantation techniques. However, novel technologies are needed to further advance the field of mechanical circulatory support Commentaries on pages 33 and Commentaries on pages 33 and is defined as the production, adoption, or integration of a value-added novelty.1Schumpeter J.A. Opie R. Elliott J.E. The Theory of Economic Development: An Inquiry into Profits, Capital, Credit, Interest, and the Business Cycle. Transaction Publishers, New Brunswick, NJ1983Google Scholar The most common definitions of innovations describe 4 subtypes in which innovations can be categorized: (1) basic research, (2) breakthrough innovation, (3) sustaining innovation, and (4) disruptive innovation.1Schumpeter J.A. Opie R. Elliott J.E. The Theory of Economic Development: An Inquiry into Profits, Capital, Credit, Interest, and the Business Cycle. Transaction Publishers, New Brunswick, NJ1983Google Scholar,2Henderson R.M. Clark K.B. Architectural innovation: the reconfiguration of existing product technologies and the failure of established firms.Adm Sci Q. 1990; 35: 9-30Crossref Google Scholar and surgical innovations are greatly interdependent, and some medical specialties, such as mechanical circulatory support (MCS) systems, are especially technology-driven. Habitually innovative developments, such as the miniaturization of devices, lead to the establishment of new implantation strategies. Contrarily, the constant longing of physicians for solutions for surgical or clinical challenges and patients' preferences drive engineers to adapt and reinvent technological breakthrough innovation in the development of MCS was the shift from pulsatile-flow to continuous-flow pumps, which facilitated the miniaturization of ventricular assist devices (VADs).3Hanke J.S. of the Google Scholar the of devices to the new generation of devices has the of the implantation and has facilitated implantation as a sustaining J.S. of the Google of a as a ventricular assist a Google ventricular assist Google of a for a ventricular assist the clinical Google Scholar The of technological devices, implantation and greatly to the of the new generation of and in the for a in Google Scholar innovative as as surgical for implantation and the the most for implantation was a a for the techniques. has the most in and has the a in Google Scholar However, the of the the of the the miniaturization of the development of J.S. of the Google of a for a ventricular assist the clinical Google for implantation of Google of a surgical for implantation of ventricular assist devices in on Google of ventricular assist implantation on of (3) Google most a of a and a the the J.S. of the Google of a as a ventricular assist a Google ventricular assist Google of a for a ventricular assist the clinical Google Scholar is the of and a J.S. of the Google for implantation of Google ventricular assist implantation Google Scholar and of implantation are in and of ventricular assist to in and for and on in a new of implantation is the of the from the in to and of Scholar in the such as the innovative implantation J.S. of the Google of a as a ventricular assist a Google ventricular assist Google Scholar is the most and the the of the in ventricular assist Google patients' for multiple implantation is failure and of of and especially in is to be a in and to in J.S. of the Google of a for a ventricular assist 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