In Vitro, In Vivo and Ex Vivo Models for Peripheral Nerve Injury andRegeneration
Andrew Li, Clifford Pereira, Elise Eleanor Hill, Olivia Vukcevich, Aijun Wang
Abstract
Peripheral Nerve Injuries (PNI) frequently occur secondary to traumatic injuries. Recovery from these injuries can be expectedly poor, especially in proximal injuries. In order to study and improve peripheral nerve regeneration, scientists rely on peripheral nerve models to identify and test therapeutic interventions. In this review, we discuss the best described and most commonly used peripheral nerve models that scientists have and continue to use to study peripheral nerve physiology and function.
Topics & Concepts
Peripheral nerveMedicinePeripheralEx vivoRegeneration (biology)Peripheral nerve injuryIn vivoPathologyNerve injuryPeripheral nervous systemEpineurial repairNeuroscienceAnatomyTraumatic injuryAnesthesiaNerve injury and regenerationNerve Injury and RehabilitationNeuroscience and Neural Engineering