Litcius/Paper detail

The road to death: Caspases, cleavage, and pores

Vishva M. Dixit

2023Science Advances19 citationsDOIOpen Access PDF

Abstract

Vishva Dixit recounts his favorite discoveries after 30-plus years studying the proteins that allow infected, damaged, or obsolete cells to die.

Topics & Concepts

CaspaseCleavage (geology)ApoptosisCell biologyChemistryProgrammed cell deathBiophysicsBiologyBiochemistryPaleontologyFracture (geology)Inflammasome and immune disordersCell death mechanisms and regulationErythrocyte Function and Pathophysiology