Design, synthesis, bioevaluation, DFT, docking, and molecular dynamic simulation for selected novel 1,3,4-Oxadiazole - indole derivatives hybrid against estrogen receptor alpha
Vasappanavara Sreenatha, Sudhanva M. Srinivasa, Karnam Jayarampillai Rajendra Prasad
Topics & Concepts
ChemistryEstrogen receptor alphaEstrogen receptorOxadiazoleTamoxifenDocking (animal)Selective estrogen receptor modulatorIndole testStereochemistryBreast cancerCancerOrganic chemistryInternal medicineNursingMedicineSynthesis and biological activitySynthesis and Biological EvaluationBioactive Compounds and Antitumor Agents