Catalyst- and Oxidizing Reagent-Free Electrochemical Benzylic C(sp<sup>3</sup>)–H Oxidation of Phenol Derivatives
Zhong‐Wei Hou, Mingming Zhang, Wenchao Yang, Lei Wang
Abstract
)-H oxidation reaction of phenol derivatives along with hydrogen evolution has been developed. The protocol proceeds in an easily available undivided cell at room temperature under catalyst- and oxidizing reagent-free conditions. The corresponding aryl aldehydes and ketones are obtained in satisfactory yields, and the gram-scale synthesis is easy to be carried out.
Topics & Concepts
Oxidizing agentReagentCatalysisPhenolChemistryElectrochemistryArylCombinatorial chemistryOrganic chemistryElectrodePhysical chemistryAlkylOxidative Organic Chemistry ReactionsRadical Photochemical ReactionsCatalytic C–H Functionalization Methods