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Protective antibodies and T cell responses to Omicron variant after the booster dose of BNT162b2 vaccine

Paul Naaber, Liina Tserel, Kadri Kangro, Marite Punapart, Epp Sepp, Virge Jürjenson, Jaanika Kärner, Liis Haljasmägi, Uku Haljasorg, Marilin Kuusk, Eve Sankovski, Anu Planken, Mart Ustav, Eva Žusinaite, Joachim M. Gerhold, Kai Kisand, Pärt Peterson

2022Cell Reports Medicine23 citationsDOIOpen Access PDF

Abstract

T cells to the wild-type and Omicron variant are detectable in the majority of vaccinated individuals. Our data show that the third dose restores the high levels of blocking antibodies and enhances T cell responses to Omicron.

Topics & Concepts

Booster (rocketry)Booster doseVirologyAntibodyAntibody responseMedicineImmunologyImmunizationPhysicsAstronomySARS-CoV-2 and COVID-19 ResearchCAR-T cell therapy researchBacillus and Francisella bacterial research
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