<i>In silico</i>study of natural compounds from sesame against COVID-19 by targeting M<sup>pro</sup>, PL<sup>pro</sup>and RdRp
Ahmed E. Allam, Yhiya Amen, Ahmed Ashour, Hamdy K. Assaf, Heba Ali Hassan, Islam M. Abdel-Rahman, Ahmed M. Sayed, Kuniyoshi Shimizu
Abstract
. All the compounds were investigated for their ADME and drug likeness properties, which showed acceptable ADME properties and obeying Lipinski's rule of five parameters. It can be concluded that the isolated compounds from sesame lignans could be an alternative source for the development of new natural leads against COVID-19.
Topics & Concepts
In silicoCoronavirus disease 2019 (COVID-19)ChemistryBiochemistryGeneMedicineDiseasePathologyInfectious disease (medical specialty)Sesame and Sesamin ResearchGarlic and Onion StudiesMetal complexes synthesis and properties