Structure of the sodium-dependent phosphate transporter reveals insights into human solute carrier SLC20
Jia‐Yin Tsai, C. K. Chu, Min-Guan Lin, Ying‐Hsuan Chou, Ruei-Yi Hong, Cheng-Yi Yen, Chwan‐Deng Hsiao, Yuh‐Ju Sun
Abstract
PiT provides a framework for understanding PiT dysfunction and for future structure-based drug design.
Topics & Concepts
TransporterSolute carrier familySodiumPhosphateChemistryFunction (biology)Sodium phosphatesBiophysicsBiochemistryBiologyCell biologyOrganic chemistryGeneParathyroid Disorders and TreatmentsAmino Acid Enzymes and MetabolismIon Transport and Channel Regulation