Gold nanoplates with superb photothermal efficiency and peroxidase-like activity for rapid and synergistic antibacterial therapy
Lu Yan, Jie Mu, Pengxin Ma, Qian Li, Pengxue Yin, Xuan Liu, Yuanyuan Cai, Haipeng Yu, Junchong Liu, Guoqing Wang, Aihua Liu
Abstract
Gold nanoplates (AuNPTs) exhibit outstanding photothermal conversion efficiency (68.5%) and peroxidase-like activity. The combination of the very low H2O2 concentration (0.1 mM) and the low AuNPT dosage (50 μg mL-1) with 808 nm laser irradiation (1 W cm-2, 3 min) shows excellent synergistic antibacterial ability and healing of MRSA-infected wounds in vivo.
Topics & Concepts
Photothermal therapyNuclear chemistryPeroxidaseChemistryNanotechnologyIn vivoAntibacterial activityPhotothermal effectMaterials scienceEnzymeBacteriaOrganic chemistryGeneticsBiologyBiotechnologyNanoplatforms for cancer theranosticsAdvanced Nanomaterials in CatalysisAdvanced biosensing and bioanalysis techniques