Systematic development and characterization of inhalable dry powder containing Polymeric Lipid Hybrid Nanocarriers co-loaded with ABCB1 shRNA and docetaxel using QbD approach
Denish Bardoliwala, Vivek Patel, Ambikanandan Misra, Krutika Sawant
Topics & Concepts
Box–Behnken designNanocarriersMaterials scienceQuality by DesignDry-powder inhalerPlackett–Burman designParticle sizeChromatographyNanotechnologyNanoparticleChemistryInhalerResponse surface methodologyMedicinePhysical chemistryInternal medicineAsthmaInhalation and Respiratory Drug DeliveryAdvanced Drug Delivery SystemsDrug Solubulity and Delivery Systems