Preparation and optimization of nano-sized cocrystals using a quality by design approach
Pradip Thakor, Balvant Yadav, Sheela Modani, Nalini R. Shastri
Abstract
Nano-cocrystals were optimized using the L-18 Hunter design. Selection of solvent and antisolvent was made using the Damkohler number.
Topics & Concepts
Quality by DesignNano-Materials scienceSolventSelection (genetic algorithm)Quality (philosophy)NanotechnologyProcess engineeringChemical engineeringComputer scienceChemistryEngineeringOrganic chemistryComposite materialArtificial intelligencePhysicsQuantum mechanicsParticle sizeCrystallization and Solubility StudiesCrystallography and molecular interactionsThermal and Kinetic Analysis