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Bone marrow mesenchymal stem cell-derived exosomes inhibit chondrocyte apoptosis and the expression of MMPs by regulating Drp1-mediated mitophagy

Sen Tang, Tao Tang, Guicheng Gao, Qiangqiang Wei, Kuo Sun, Wenzhou Huang

2021Acta Histochemica38 citationsDOI

Topics & Concepts

Mesenchymal stem cellMicrovesiclesMitophagyCell biologyAutophagyApoptosisChemistryMatrix metalloproteinaseExosomeChondrocyteBone marrowDNM1LCartilageBiologyImmunologyMitochondrionMitochondrial fissionmicroRNAAnatomyBiochemistryGeneOsteoarthritis Treatment and MechanismsExtracellular vesicles in diseaseLower Extremity Biomechanics and Pathologies
Bone marrow mesenchymal stem cell-derived exosomes inhibit chondrocyte apoptosis and the expression of MMPs by regulating Drp1-mediated mitophagy | Litcius