Litcius/Paper detail

Dynamically reconfigurable acoustofluidic metasurface for subwavelength particle manipulation and assembly

Sushruta Surappa, Suraj Pavagada, Fernando Soto, Demir Akin, Charles Wei, F. Levent Degertekin, Utkan Demirci

2025Nature Communications28 citationsDOIOpen Access PDF

Abstract

Particle manipulation plays a pivotal role in scientific and technological domains such as materials science, physics, and the life sciences. Here, we present a dynamically reconfigurable acoustofluidic metasurface that enables precise trapping and positioning of microscale particles in fluidic environments. By harnessing acoustic-structure interaction in a passive membrane resonator array, we generate localized standing acoustic waves that can be reconfigured in real-time. The resulting radiation force allows for subwavelength manipulation and patterning of particles on the metasurface at individual and collective scales, with actuation frequencies below 2 MHz. We further demonstrate the capabilities of the reconfigurable metasurface in trapping and enriching beads and biological cells flowing in microfluidic channels, showcasing its potential in high-throughput bioanalytical applications. Our versatile and biocompatible particle manipulation platform is suitable for applications ranging from the assembly of colloidal particles to enrichment of rare cells.

Topics & Concepts

Particle (ecology)Computer scienceNanotechnologyPhysicsMaterials scienceBiologyEcologyMicrofluidic and Bio-sensing TechnologiesOrbital Angular Momentum in OpticsNear-Field Optical Microscopy