Inhibition of the NLRP3 inflammasome with MCC950 prevents chronic social isolation-induced depression-like behavior in male mice
Wei Li, Lei Niu, Zhenghai Liu, Xuan Xu, Mengmeng Shi, Yuan Zhang, Yingcheng Deng, Jie He, Yang Xu, Wei Wan, Qiumin Sun, Xiaolin Zhong, Wenyu Cao
Topics & Concepts
Hippocampal formationInflammasomeAntidepressantSocial isolationHippocampusSocial defeatDepression (economics)Chronic stressReceptorPsychologyNeuroscienceMedicineInternal medicinePsychiatryEconomicsMacroeconomicsTryptophan and brain disordersStress Responses and CortisolNeuroendocrine regulation and behavior