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Electron‐Rich Oxycarbenes: New Synthetic and Catalytic Applications beyond Group 6 Fischer Carbene Complexes

Gang Zhou, Zhuanzhuan Guo, Xiao Shen

2023Angewandte Chemie International Edition67 citationsDOIOpen Access PDF

Abstract

Oxycarbenes have emerged as useful intermediates in synthetic chemistry. Compared to the widely studied oxycarbene metal complexes bearing Group 6 metals, the synthetic and catalytic applications of oxycarbenes beyond Group 6 Fischer carbene complexes are less explored because of the difficulty in controlling their reactivity and the need to use a stoichiometric amount of a presynthesized Group 6 metal carbene complex as the starting material. This Minireview summarizes early synthetic and catalytic applications of late-transition-metal oxycarbene complexes and highlights recent advances in free oxycarbene reactions and transition-metal-catalyzed reactions involving oxycarbenes. We hope this Minireview will inspire further developments in this emerging area.

Topics & Concepts

CarbeneCatalysisTransition metalMain group elementReactivity (psychology)ChemistryCombinatorial chemistryGroup (periodic table)MetalStoichiometryNanotechnologyMaterials scienceOrganic chemistryAlternative medicineMedicinePathologyCyclopropane Reaction MechanismsCatalytic Alkyne ReactionsCatalytic Cross-Coupling Reactions
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