Phenanthridine based fluorescent probe for Th4+ ion chemosensor
Shanthi Seenan, Saravanakumar Manickam, Sathish Sawminathan, Dhanapal Jothi, Sathiyanarayanan Kulathu Iyer
Abstract
A benzhydrylpiperazine-based phenanthridine ( 5a ) moiety has been developed as a ratiometric fluorescence and colorimetric probe for the detection of Th 4+ ion. After the addition of Th 4+ ion, probe 5a was immediately color-altered from blue to yellow fluorescence with an emission maximum at 560 nm. Probe 5a showed superior selectivity and sensitivity towards Th 4+ ions over the other competitive metal ions. This sensor probe exhibited a lower detection limit (2.76 nM). Then through the 1 H NMR titration experiment, it was confirmed that the benzhydrylpiperazine moiety of 5a was chelated with Th 4+ ion. However, probe 5a was utilized for the detection of Th 4+ ion in real water samples and monazite sand. Most importantly, the application of this sensor probe 5a for the recognition of Th 4+ ion in E. coli cells had been successful.