A homotetrameric hemoglobin expressed in alveolar epithelial cells increases blood oxygenation in high-altitude plateau pika (Ochotona curzoniae)
Zhifang An, Linna Wei, Bo Xu, Zhijie Wang, Conghui Gao, Jimei Li, Lian Wei, Delin Qi, Peng Shi, Tongzuo Zhang, Dengbang Wei
Abstract
. These findings provide insights into the adaptive mechanisms of plateau pikas to withstand high-altitude environments.
Topics & Concepts
PikaHemoglobinBiologyPlateau (mathematics)Effects of high altitude on humansHypoxia (environmental)HypoxemiaLungCell biologyMolecular biologyAnatomyOxygenChemistryInternal medicineEcologyBiochemistryMedicineMathematicsNational parkOrganic chemistryMathematical analysisHemoglobin structure and functionNeuroscience of respiration and sleepHigh Altitude and Hypoxia