The Yersinia high-pathogenicity island encodes a siderophore-dependent copper response system in uropathogenic Escherichia coli
George L. Katumba, Hung D. Tran, Jeffrey P. Henderson
Abstract
Siderophores are iron chelators used by microbes to bind and acquire iron, which, once in the cell, inhibits siderophore production through feedback repression mediated by the ferric uptake repressor (Fur). Yersiniabactin (Ybt), a siderophore associated with enhanced pathogenic potential among
Topics & Concepts
MicrobiologyPathogenicitySiderophorePathogenicity islandEscherichia coliBiologyYersiniaEnterobacteriaceaeBacteriaCopperVirologyChemistryGeneticsGeneOrganic chemistryYersinia bacterium, plague, ectoparasites researchAntibiotic Resistance in BacteriaTrace Elements in Health