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Thiazol-4(5H)-one analogs as potent tyrosinase inhibitors: Synthesis, tyrosinase inhibition, antimelanogenic effect, antioxidant activity, and in silico docking simulation

Yu Jung Park, Hee Jin Jung, Hye Jin Kim, Hye Soo Park, Jieun Lee, Dahye Yoon, Min Kyung Kang, Ga Young Kim, Sultan Ullah, Dongwan Kang, Yujin Park, Pusoon Chun, Hae Young Chung, Hyung Ryong Moon

2023Bioorganic & Medicinal Chemistry16 citationsDOIOpen Access PDF

Topics & Concepts

TyrosinaseKojic acidChemistryArbutinAntioxidantDocking (animal)StereochemistryTroloxDPPHABTSKnoevenagel condensationIC50BiochemistryEnzymeIn vitroNursingMedicineCatalysismelanin and skin pigmentationBiochemical Analysis and Sensing TechniquesSkin Protection and Aging
Thiazol-4(5H)-one analogs as potent tyrosinase inhibitors: Synthesis, tyrosinase inhibition, antimelanogenic effect, antioxidant activity, and in silico docking simulation | Litcius