Hypervalent iodine(<scp>iii</scp>)-mediated oxidative dearomatization of 2<i>H</i>-indazoles towards indazolyl indazolones
Suvam Bhattacharjee, Sudip Laru, Alakananda Hajra
Abstract
-1 indazolyl indazolones. In this methodology, PIFA plays a dual role: as an oxidant and as a carbonyl oxygen source. A series of indazolone derivatives was promptly synthesized in good to excellent yields through sequential C-heteroatom bond formation. Mechanistic studies indicate that the reaction likely takes place through an SET pathway.
Topics & Concepts
Hypervalent moleculeIodineChemistryOxidative phosphorylationBiochemistryOrganic chemistryOxidative Organic Chemistry ReactionsCatalytic C–H Functionalization MethodsSynthesis and Catalytic Reactions