A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis
Jin Qian, Chenkai Ma, Quin T. Waterbury, Xiaofei Zhi, Christine S. Moon, Ruhong Tu, Hiroki Kobayashi, Feijing Wu, Biyun Zheng, Yi Zeng, Hualong Zheng, Yosuke Ochiai, Ruth A. White, David W. Harle, Jonathan S. LaBella, Leah Zamechek, Lucas ZhongMing Hu, Ryan H. Moy, Arnold Han, Bruce L. Daugherty, Seth Lederman, Timothy C. Wang
Topics & Concepts
GranulopoiesisAgonistCancer immunotherapyImmunologyImmunotherapyCancerMedicineCancer researchHaematopoiesisBiologyReceptorInternal medicineImmune systemCell biologyStem cellChemokine receptors and signalingImmune cells in cancerImmunotherapy and Immune Responses