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Profile of Immunoglobulin G and IgM Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Jiuxin Qu, Chi Wu, Xiaoyong Li, Guobin Zhang, Zhaofang Jiang, Xiaohe Li, Qing Zhu, Lei Liu

2020Clinical Infectious Diseases332 citationsDOIOpen Access PDF

Abstract

We profiled the serological responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein and spike (S) glycoprotein. The majority of the patients developed robust antibody responses between 17 and 23 days after illness onset. Delayed, but stronger, antibody responses were observed in critical patients.

Topics & Concepts

MedicineSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)AntibodyCoronavirus disease 2019 (COVID-19)Immunoglobulin MImmunology2019-20 coronavirus outbreakImmunoglobulin GVirologyCoronavirusRespiratory systemPathologyOutbreakInternal medicineInfectious disease (medical specialty)DiseaseSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19