Inactive and active state structures template selective tools for the human 5-HT5A receptor
Shicheng Zhang, He Chen, Chengwei Zhang, Yang Ying, Petr Popov, Jing Liu, B. Krumm, Can Cao, Kuglae Kim, Yan Xiong, Vsevolod Katritch, Brian K. Shoichet, Jian Jin, Jonathan F. Fay, Bryan L. Roth
Topics & Concepts
ReceptorAgonistSerotonergicDrug discoveryPartial agonistAntagonistComputational biologyCompetitive antagonistCell biologyBiologyChemistrySerotoninBioinformaticsBiochemistryReceptor Mechanisms and SignalingPharmacogenetics and Drug MetabolismAnalytical Chemistry and Chromatography