Periodate Oxidation of Carboxymethyl Cellulose under Controlled Conditions
Yunfeng Zhang, Linlin Zhang, Shengjuan Shao, Xiliang Chang, Min Li
Abstract
Abstract In this study, we synthesized dialdehyde carboxymethyl cellulose (DCMC) based on the oxidation reaction of periodate (i. e., Malaprade reaction) in acidic conditions. The primary factors on the synthesis of DCMC were explored based on a 3×3 orthogonal optimization experiment using the reaction temperature, material ratio, and pH, as variables. we identified an optimum DCMC synthetic condition based on the analysis of the production yield and aldehyde content in the final product. The results showed that the impacts of the three factors on the synthesis of DCMC adhered to the order of pH > temperature > material ratio. Synthesis conditions involved pH value of 3.0, reaction temperature of 30 °C, a mass ratio of NaIO 4 and CMC of 1 : 1, and a reaction time of 4 h. Which yielded a dialdehyde DCMC content of 79.04 %. By characterizing the carboxymethyl cellulose (CMC) and DCMC samples with Fourier‐transform infrared spectroscopy, X‐ray diffraction, thermogravimetric analysis, and scanning electron microscopy, we confirmed the production of DCMC from the reaction and the crystallinity and thermal stability of CMC reduced when it was oxidized to DCMC.