Peripheral apelin mediates visceral hypersensitivity and impaired gut barrier in a rat irritable bowel syndrome model
Tsukasa Nozu, Saori Miyagishi, Masatomo Ishioh, Kaoru Takakusaki, Toshikatsu Okumura
Topics & Concepts
Irritable bowel syndromeInternal medicineApelinEndocrinologyVisceral painMedicineProinflammatory cytokineReceptor antagonistTLR4AgonistAntagonistReceptorInflammationNociceptionApelin-related biomedical researchCardiovascular, Neuropeptides, and Oxidative Stress ResearchHormonal Regulation and Hypertension