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Species interactions, stability, and resilience of the gut microbiota - Helminth assemblage in horses

Michel Boisseau, Sophie Dhorne‐Pollet, David Bars‐Cortina, Élise Courtot, Delphine Serreau, Gwenolah Annonay, Jérôme Lluch, Amandine Gesbert, Fabrice Reigner, Guillaume Sallé, Núria Mach

2023iScience28 citationsDOIOpen Access PDF

Abstract

. They exhibited a highly diverse and temporal dynamic gut microbiota, with butyrate-producing Clostridia likely driving the ecosystem steadiness and host tolerance toward cyathostomins infection. However, anthelmintic administration sharply bent the microbial community. It disrupted the ecosystem stability and the time-dependent network of interactions, affecting longer term microbial resilience. These observations highlight how anthelmintic treatments alter the triangular relationship of parasite, host, and gut microbiota and open new perspectives for adding nutritional intervention to current parasite management strategies.

Topics & Concepts

BiologyGut floraHost (biology)EcologyEcosystemHeligmosomoides polygyrusHelminthsZoologyImmunologyHelminth infection and controlPlant and fungal interactionsGut microbiota and health