Inhibitors of ERp44, PDIA1, and AGR2 induce disulfide-mediated oligomerization of Death Receptors 4 and 5 and cancer cell death
Mary E. Law, Elham Yaaghubi, Amanda F. Ghilardi, Bradley J. Davis, Renan B. Ferreira, Jin Koh, Sixue Chen, Sadie F. DePeter, Christopher M. Schilson, Chi‐Wu Chiang, Coy D. Heldermon, Peter Nørgaard, Ronald K. Castellano, Brian K. Law
Topics & Concepts
Epidermal growth factor receptorDownregulation and upregulationProgrammed cell deathCancer cellCancerReceptorChemistryCell biologyCancer researchApoptosisBiologyBiochemistryGeneticsGeneEndoplasmic Reticulum Stress and DiseaseAdenosine and Purinergic SignalingAutophagy in Disease and Therapy