Linolenic acid ameliorates sarcopenia in <i>C. elegans</i> by promoting mitophagy and fighting oxidative stress
Lu Zhang, Xueyi Zhang, Tao Zhang, Yiwen Guo, Wenjun Pei, Ruijie Liu, Ming Chang, Xingguo Wang
Abstract
and DAF-16/FOXO transcription factors, respectively, by linolenic acid. This study could provide some evidence for the application of n-3 PUFA in improving sarcopenia.
Topics & Concepts
MitophagySarcopeniaCaenorhabditis elegansOxidative stressPolyunsaturated fatty acidLinolenic acidBiologyBiochemistryFatty acidChemistryEndocrinologyAutophagyGeneLinoleic acidApoptosisNutrition and Health in AgingGenetics, Aging, and Longevity in Model OrganismsDiet and metabolism studies