A case report of ChAdOx1 nCoV-19 vaccine–associated encephalitis
Junko Takata, Simon M Durkin, Solomon Wong, Michael S. Zandi, Josephine Swanton, Tumena Corrah
Abstract
BACKGROUND: Vaccination against COVID-19 continues apace, but side-effects, both common and severe, continue to be reported. We report here the first published case of COVID-19 vaccine-related encephalitis. CASE PRESENTATION: A young woman presented with acute neuropsychiatric symptoms following recent ChAdOx1 nCoV-19 vaccination. Extensive investigation did not identify alternative causes. CONCLUSIONS: This difficult case is here described, including presentation, investigation, and management. Further study on neuropsychiatric side-effects of COVID-19 vaccination, including investigation as to whether there may be a causal link, is required.
Topics & Concepts
MedicineVaccinationCoronavirus disease 2019 (COVID-19)EncephalitisNeurologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PandemicNeurosurgeryNeurochemistry2019-20 coronavirus outbreakPediatricsVirologyImmunologyDiseaseSurgeryPathologyPsychiatryInfectious disease (medical specialty)VirusOutbreakSARS-CoV-2 and COVID-19 ResearchLong-Term Effects of COVID-19Peripheral Neuropathies and Disorders