HLA class II immunogenic mutation burden predicts response to immune checkpoint blockade
Xiangqi Shao, Justin Huang, Noushin Niknafs, Archana Balan, Christopher Cherry, James R. White, Victor E. Velculescu, Valsamo Anagnostou, Rachel Karchin
Topics & Concepts
Human leukocyte antigenMedicineMelanomaImmune checkpointContext (archaeology)ImmunotherapyImmunologyHLA-CLung cancerCancerCancer researchOncologyImmune systemAntigenInternal medicineBiologyPaleontologyCancer Immunotherapy and BiomarkersImmunotherapy and Immune Responsesvaccines and immunoinformatics approaches