Electrochemical Synthesis of Trisubstituted Oxazoles and Imines from β‐Diketones and Amines
Yangli Wang, Xiaojing Zhao, Xi Wu, Lizhu Zhang, Ganpeng Li, Yonghui He
Abstract
Abstract An electrochemical oxidation reaction was developed for the synthesis of trisubstituted oxazoles and imines. The use of external oxidant and transition‐metal catalyst was avoided in the methodology. Various trisubstituted oxazoles and imines were obtained in moderate to excellent yields. The mechanism studies propose the electrochemical reaction involves a radical process.
Topics & Concepts
ElectrochemistryChemistryCombinatorial chemistryCatalysisTransition metalReaction conditionsReaction mechanismOrganic chemistryElectrodePhysical chemistryCatalytic C–H Functionalization MethodsAsymmetric Hydrogenation and CatalysisChemical Synthesis and Analysis