Identification of isoform/domain-selective fragments from the selection of DNA-encoded dynamic library
Yu Zhou, Wenyin Shen, Jianzhao Peng, Yuqing Deng, Xiaoyu Li
Topics & Concepts
ChemistryBromodomainGene isoformDrug discoveryComputational biologyDNABRD4Fragment (logic)SirtuinPeptide libraryBiochemistryPeptide sequenceGeneHistoneBiologyAlgorithmAcetylationComputer scienceChemical Synthesis and AnalysisProtein Degradation and InhibitorsClick Chemistry and Applications