Counteraction of stability-activity trade-off of Nattokinase through flexible region shifting
Jie Luo, Chenshuo Song, Wenjing Cui, Laichuang Han, Zhemin Zhou
Topics & Concepts
Stability (learning theory)Flexibility (engineering)MutantMechanism (biology)Molecular dynamicsEnzymeChemistryComputer scienceBiochemistryPhysicsComputational chemistryGeneMathematicsStatisticsQuantum mechanicsMachine learningEnzyme Catalysis and ImmobilizationEnzyme Structure and FunctionProtein Structure and Dynamics