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Optimal control problem and backward bifurcation on malaria transmission with vector bias

Dipo Aldila, Michellyn Angelina

2021Heliyon47 citationsDOIOpen Access PDF

Abstract

. Using the Pontryagin maximum principle, the optimal control problem is constructed by treating fumigation and medical treatment parameters as the time-dependent variable. Our numerical results on the optimal control simulation suggest that time-dependent fumigation and medical treatment could suppress the spread of malaria more efficiently at minimum cost.

Topics & Concepts

Optimal controlBasic reproduction numberMathematicsFumigationBifurcationApplied mathematicsMaximum principleBifurcation theoryControl theory (sociology)Mathematical optimizationComputer scienceControl (management)BiologyPhysicsPopulationEcologyNonlinear systemSociologyDemographyArtificial intelligenceQuantum mechanicsMathematical and Theoretical Epidemiology and Ecology ModelsEvolution and Genetic DynamicsMalaria Research and Control