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The Role of Heat Shock Proteins in Insect Stress Response, Immunity, and Climate Adaptation

Davide Banfi, Tommaso Bianchi, Maristella Mastore, Maurizio Francesco Brivio

2025Insects18 citationsDOIOpen Access PDF

Abstract

Heat shock proteins (HSPs) play a key role in enhancing insect resilience to abiotic and biotic stresses by preserving cellular integrity and modulating immune responses. This review summarizes the main functions of HSPs in insects, including protein stabilization, interaction with antioxidant systems, and involvement in the innate immune response. The expression of HSPs under environmental conditions reflects their evolutionary adaptation to various stressors, including thermal changes, chemical exposure, and pathogens. Future research should focus on the interaction between HSPs and other stress response systems to improve our understanding of insect adaptation. Furthermore, in the context of global climate change, HSPs emerge as a crucial resilience factor and potential biomarkers for environmental monitoring.

Topics & Concepts

BiologyHeat shock proteinAdaptation (eye)Context (archaeology)Abiotic componentImmune systemStressorInsectInnate immune systemPhenotypic plasticityEcologyCell biologyImmunologyGeneticsNeuroscienceGenePaleontologyInsect Pest Control StrategiesHeat shock proteins researchInsect and Pesticide Research