Evaluation of the Performance of the IMMY sona <i>Aspergillus</i> Galactomannan Lateral Flow Assay When Testing Serum To Aid in Diagnosis of Invasive Aspergillosis
P. Lewis White, Jessica S. Price, Raquel Posso, Morgan Cutlan-Vaughan, Lorna Vale, Matthijs Backx
Abstract
Management of invasive aspergillosis has been improved by biomarker assays, but limited accessibility and batch testing limit the impact. Lateral flow assays (LFA) are a simple method for use outside specialist centers, provided performance is acceptable. The objective of this study was to determine the performance of the recently released IMMY sona Aspergillus LFA when testing serum samples. The study took the form of a retrospective, anonymous case/control study comprising 179 serum samples from 136 patients with invasive fungal disease, previously documented using recently revised internationally accepted definitions.
Topics & Concepts
GalactomannanAspergillosisAspergillusBiomarkerMedicineMicrobiologyBiologyInternal medicineImmunologyBiochemistryAntifungal resistance and susceptibilityFungal Infections and StudiesPlant Pathogens and Fungal Diseases