Synthesis and biological evaluation of benzofuran-based 3,4,5-trimethoxybenzamide derivatives as novel tubulin polymerization inhibitors
Qiu Li, Xie‐Er Jian, Zhi-ru Chen, Lin Chen, Xian‐Sen Huo, Zihua Li, Wen‐Wei You, Jinjun Rao, Pei‐Liang Zhao
Topics & Concepts
HeLaChemistryCytotoxicityCell cultureBenzofuranTubulinIC50Derivative (finance)StereochemistryCancer cell linesCombinatorial chemistryCancer cellCellBiochemistryIn vitroMicrotubuleCancerCell biologyBiologyFinancial economicsGeneticsEconomicsSynthesis and biological activityClick Chemistry and ApplicationsBioactive Compounds and Antitumor Agents