Novel Preclinical Study of Galloylquinic Acid Compounds from <i>Copaifera lucens</i> with Potent Antifungal Activity against Vaginal Candidiasis Induced in a Murine Model via Multitarget Modes of Action
Lamiaa A. Al-Madboly, Mohamed Abd El-Salam, Jairo K. Bastos, Safinaz H. El-Shorbagy, Rami Elmorsi
Abstract
murine model of vaginal candidiasis, GQAs further demonstrated strong evidence of their effectiveness as an antifungal therapy. In this regard, our findings provide novel insights into the potential therapeutic use of these phytoactive molecules for vaginal candidiasis treatment.
Topics & Concepts
AntifungalCandida albicansBiologyPharmacologyMicrobiologyTraditional medicineMedicineAntifungal resistance and susceptibilityEssential Oils and Antimicrobial ActivityPlant Toxicity and Pharmacological Properties