Aptamer conjugated polydopamine-coated gold nanoparticles as a dual-action nanoplatform targeting β-amyloid peptide for Alzheimer's disease therapy
Juan Qin, Yanxue Guan, Zongjia Li, Xinyue Guo, Miaomiao Zhang, Dapeng Wang, Jilin Tang
Abstract
aggregation. Taken together, this study provided a new dual-action nanoplatform for Aβ-targeted AD therapy.
Topics & Concepts
AptamerColloidal goldConjugated systemPeptideAmyloid (mycology)Amyloid βNanotechnologyTargeted therapyDiseaseMaterials scienceMedicineNanoparticleChemistryMolecular biologyBiochemistryInternal medicineBiologyPathologyCancerPolymerComposite materialAlzheimer's disease research and treatmentsNanocluster Synthesis and ApplicationsSupramolecular Self-Assembly in Materials