Syntaxin17 contributes to obesity cardiomyopathy through promoting mitochondrial Ca2+ overload in a Parkin-MCUb-dependent manner
Haixia Xu, Wenjun Yu, Mingming Sun, Yaguang Bi, Ne N. Wu, Yuan Zhou, Qi Yang, Mengjiao Zhang, Junbo Ge, Yingmei Zhang, Jun Ren
Topics & Concepts
MitochondrionDownregulation and upregulationInternal medicineEndocrinologyHEK 293 cellsCardiomyopathyHomeostasisCell biologyOxidative stressCaveolaeTransfectionChemistryHeart failureBiologyMedicineSignal transductionBiochemistryReceptorGeneMitochondrial Function and PathologyAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and Disease