A chromosome-scale genome assembly of Rauvolfia tetraphylla facilitates identification of the complete ajmaline biosynthetic pathway
Enzo Lezin, Inês Carqueijeiro, Clément Cuello, Mickaël Durand, Hans J. Jansen, Valentin Vergès, Caroline Birer-Williams, Audrey Oudin, Thomas Dugé de Bernonville, Julien Pétrignet, Noémie Celton, Benoit St‐Pierre, Nicolas Papon, Chao Sun, Ron P. Dirks, Sarah E. O’Connor, Michael K. Jensen, Sébastien Besseau, Vincent Courdavault
Abstract
Figure 1.Chromosome-scale genome of R. tetraphylla and identification of 1,2-dihydrovomilenine reductase.(A) Genomic landscape of R. tetraphylla.Concentric rings present, from the outside to the inside, pseudo-chromosome name, pseudo-chromosome scale, gene density (purple: low density; yellow: high density)
Topics & Concepts
AjmalineComputational biologyIdentification (biology)BiologyGenomeChromosomeGeneticsBotanyGeneNeuroscienceAlkaloids: synthesis and pharmacologyPhytochemistry and Biological ActivitiesNatural product bioactivities and synthesis