IL-27 Negatively Regulates Tip-DC Development during Infection
Gongguan Liu, Osama Abas, Yong Fu, Yanli Chen, Ashley B. Strickland, Donglei Sun, Meiqing Shi
Abstract
monocytes. These findings delineate an in-depth view of mechanisms of Tip-DC differentiation that may have significant implications for the ongoing development of IL-27-based immunotherapy.
Topics & Concepts
Cell biologyTumor necrosis factor alphaImmunologyImmune systemInflammationDendritic cellBiologyCytokineInterleukin 10MonocyteImmune Cell Function and InteractionCytokine Signaling Pathways and InteractionsAutoimmune and Inflammatory Disorders Research