N-acetylserotonin derivative ameliorates hypoxic-ischemic brain damage by promoting PINK1/Parkin-dependent mitophagy to inhibit NLRP3 inflammasome-induced pyroptosis
Fang Fang, Jiaxin Tang, Jiaqing Geng, Chengzhi Fang, Bing‐Hong Zhang
Topics & Concepts
ParkinMitophagyPyroptosisInflammasomePINK1AutophagyChemistryNeuroinflammationCell biologyMedicinePharmacologyInflammationNeuroscienceBiologyApoptosisImmunologyInternal medicineBiochemistryDiseaseParkinson's diseaseInflammasome and immune disordersHeme Oxygenase-1 and Carbon MonoxideNeuroscience of respiration and sleep